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KMID : 0616620090150010059
Journal of Soonchunhyang Medical College
2009 Volume.15 No. 1 p.59 ~ p.65
Analysis of the Admission Characteristics of Patients Adn-iitted for Acute Hepatitis A during the Last 5 Years
Jang Jae-Young

Yoo Byung-Wook
Oh Jung-Eun
Cho Choo-Yon
Hong Sung-Ho
Cho Yong-Jin
Abstract
Background:Due to improvements in Korea¡¯s sanitary conditions, antibody rates to the hepatitis A virus is decreasing rapidly and admission due to the disease is increasing, Patients who were admitted for hepatitis A during the last 5 years were selected and yearly differences in admission, clinical picture, medical fees, and differences according to age and gender were analyzed.

Methods:Patients who were admitted to the Seoul Soonchunhyang University Hospital during the 5 year period between May of 2003 and April of 2008 and tested positive for IgM anti-HAV were selected and their medical records retrospectively analyzed.

Results:156 subjects [91 male (58%), 65 female (42%) were selected. The average age was 29.2 years (range; 21.4-37), average admission period 12.6 days (range; 12.5-1 7.7) days, and average medical fees 2,295,151 (range; 932,097-3,658,205) KRW(Korean Won), Yearly incidence rates were as follows : 10 for May, 2003 to April, 2004, 14 for May, 2004 to April, 2005, 23 for May, 2005 to April, 2006, 69 for May, 2006 to April, 2007, and 41 for May, 2007 to April, 2008, The maximum value median of AST, ALT, and bilirubin during admission was 989 IU/L, 1999 IU/L, and 5.6 mg/dL each, Each factors were all positively correlated with the patient¡¯s age.

Conclusions:Recent decrease in antibody positivity of the hepatitis A virus and subsequent surge of acute
hepatitis A is a cause of rising socioeconomic costs. A large scale epidemiologic research on whether HAV vaccination should be made mandatory and health insurance applied seems to be needed.
KEYWORD
Hepatitis A, Age, Medical fees, Vaccination
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